A multicentre study to determine the efficacy and patient acceptability of scalp cooling in the prevention of docetaxel-induced hair loss

INTERVENTION: Scalp cooling with various cooling times or cooling temperatures. CONDITION: Hair loss due to chemotherapy ; Cancer ; Cancer, hair loss PRIMARY OUTCOME: Efficacy and patient acceptability of scalp cooling. SECONDARY OUTCOME: Relation of the efficacy of scalp cooling and:; 1. Prior treatment with cytostatic agents; 2. Prior or parallel hormonal treatment; 3. Prior radiotherapy of the scalp; 4. Liver metastases and/or liver or kidney function disorder; 5. Type of hair (determined by race) INCLUSION CRITERIA: 1. Intravenous administered docetaxel regimes 2. Age 18 years or more 3. Written informed consent