Neurosensory analysis of tooth sensitivity during at-home dental bleaching

Category Primary study
Registry of TrialsBrazilian Registry of Clinical Trials
Year 2016
INTERVENTION: E06.420.750 It was used the split mouth design in the present study. Twenty five patients were submitted to two types of at‐home bleaching products, one in the right maxilar hemi‐arch and the other in the left one. Thus, dental arch impressions were taken using alginate in order to obtain stone molds. In the molds, individual acetate trays were fabricated. In one maxilar hemi‐arch, patients used a bleaching product based on 10% carbamide peroxide containning potassium oxalate, a desensitizing agent. In the other maxilar hemi‐arch, another at‐home bleaching product based on 10% carbamide peroxide with no desensitizing agent was used. Both products were applied using the acetate tray, during 4 daily hours, for 3 weeks. CONDITION: C07.793.266 Dental sensitivity ; C07.793.266 PRIMARY OUTCOME: The actually observed outcome was the intensity of tooth sensitivity (in degrees Celsius) recorded before, 7 days, 14 days and 21 days after the beginning of the bleaching treatments. The method used was the Quantitative Sensory Testing, which by means of a descending cold temperature transmitter positioned on the buccal surface of the tooth, provided accurate cold temperature detection by the patient. In the group bleached using 10% carbamide peroxide with potassium oxalate (desensitizing) it was observed an increase in the intensity of tooth sensitivity 7 days (16.69) 14 days (16.73) and 21 days (16.07) after the treatment, when compared with the initial values ??(11.44).; In the group bleached using 10% carbamide peroxide without the addition of desensitizing, there was also an increase in the intensity of tooth sensitivity 7 days (15.77) 14 days (16.56) and 21 days (15.92) after the treatment, when compared to baseline (11.31).; Thus, among the initial values ??of both groups and the values ??of times 7, 14 and 21 days there was no statistically significant difference (p <0.05), showing that the desensitizing product was not effective in reducing the intensity of tooth sensitivity. The expected primary outcome is the intensity of tooth sensitivity. By means of the quantitative sensory method and the use of cold temperature transmitter on the tooth surface connected to a computer software. A variation of at least 5% was used in temperature changes before and after the use of the bleaching product. SECONDARY OUTCOME: No secondary outcomes were observed. INCLUSION CRITERIA: Volunteers with healthy and vital maxillary teeth; no decayed teeth; no visible enamel defects; no orthodontic brackets; overall good systemic health; healthy oral soft tissue; non‐smoking; pacients who have never undergone bleaching treatment.
Epistemonikos ID: 31fdd47c1433585210b8eebad0e59c58dd61334f
First added on: Aug 24, 2024