Dynamic brain characterization research on central sensitization of migraine and therapeutic effect prediction

INTERVENTION: true accupuncture of patients:accupuncture at taichong (baseline);sham accupuncture of patients:shame accupuncture at taichong (baseline);ture acupuncture of healthy controls:true accupuncture at taichong; CONDITION: migraine PRIMARY OUTCOME: Central sensitization inventory;Massachusetts Hospital Acupuncture Sensory ScaleC‐MASS; SECONDARY OUTCOME: functional magnetic resonance imaging data,fMRI data;Numerical Rating Scale;Headache Impact Test‐6, HIT‐6;Migraine Disability Assessment MIDAS; INCLUSION CRITERIA: migraineur INCLUSION CRITERIA:1.Met the diagnostic criteria for migraine and had no other primary or secondary causes of headache; 2. The duration of the disease is longer than 3 months and the frequency of headache is not less than 15 times per month; 3.Age: 18‐65 years old; 4. Right‐handed; 5.Have not received electroacupuncture treatment or other preventive treatment for nearly 1 month and have no long‐term habit of taking analgesic drugs; 6. Hamilton depression ‐24 score no higher than 35 and Hamilton anxiety ‐14 score less than 21; 7.No experience of acupuncture and similar therapies.