epinephrine in COVID-19

INTERVENTION: Intervention 1: Intervention group: The standard treatment for COVID‐19 based on the Ministry of Health's protocol plus intratracheal epinephrine for intubated patients, and nebulizer form of epinephrine for non‐intubated patients at a dose of 200 micrograms three times a day for five days. Intervention 2: Control group: The standard treatment for COVID‐19 based on the Ministry of Health's protocol plus intratracheal or nebulizer distilled water at a same volume three times a day for five days. CONDITION: COVID‐19, virus identified. ; COVID‐19, virus identified U07.1 PRIMARY OUTCOME: Clinical symptoms. Timepoint: Before intervention and daily during the study. Method of measurement: Questionnaire. Oxygen saturation. Timepoint: Before intervention and daily during the study. Method of measurement: Pulse oximeter. Pulmonary imaging finding. Timepoint: Before intervention and the fifth day of the study. Method of measurement: Computed tomography. SECONDARY OUTCOME: Incidence of serious adverse events. Timepoint: Before intervention and daily during the study. Method of measurement: Questionnaire. INCLUSION CRITERIA: Age between 18 and 80 years Positive polymerase chain reaction (PCR) test for COVID‐19 Hospitalized Signing informed consent and willingness of study participant to accept randomization to any assigned treatment a