Clinical effects of budesonide/formoterol in patients with asthma

INTERVENTION: Symbicort treatment group Symicort turbuhaler (60) 2 inhlation, twice daily Treatment period 4 months Budosonide treatment group Budosonide turbuhaler (200) 2 inhlation, twice daily Treatment period 4 months CONDITION: Bronchial asthma PRIMARY OUTCOME: Indices of chest CT SECONDARY OUTCOME: Parameters of pulmonary function; PEF; Cell counts of induced sputum; Scores of quality of life INCLUSION CRITERIA: 1. Patients who have been not treated with ICS or oral corticosteroids within 2 months before the study 2. Patients who have been not treated with LABA within 1 months before the study 3. Patients have typical asthma symptoms as follows; cough, wheeze, dyspnea, nocturnal sleep disturbance