Randomized controlled trial to evaluate clinical safety and efficacy of oral immunotherapy with low dose of egg for children with egg allergy

Authors
Category Primary study
Registry of TrialsUMIN Clinical Trials Registry
Year 2011
INTERVENTION: To take small amount of egg powder masked with corn powder once daily for 25‐28 weeks To take corn powder as placebo once daily for 25‐28 weeks CONDITION: Food hypersensitivity,Food allergy PRIMARY OUTCOME: The result of double ‐blind placebo controlled food challenge test of egg after 25‐28 weeks intervention SECONDARY OUTCOME: 1)The threshold change of egg allergen dose to provoke immediate reaction before and after this intervention; 2)The change of egg specific antibody serum concentration before and after this intervention; 3)Incidence of patients who experience allergic reaction due to adverse effect of this intervention ; 4)Onset number of allergic reaction due to adverse effect of this intervention in each case INCLUSION CRITERIA: 1)Patients who keep complete elimination of egg from their diet 2)Patients who were confirmed as having egg allergy by double blind placebo controlled food challenge test 3)Egg white‐specific IgE‐positive patients 4)Patients whose family are cooperative enough to adhere to the protocol of this study
Epistemonikos ID: 3073bf6f5693510dc6ca7177ea39924f570ca2f0
First added on: Aug 22, 2024