Study on treatment and diagnosis of integrated traditional Chinese and western medicine on lung fibrosis in recovery stage of SARS

Objective: To investigate the treatment effects of integrated traditional Chinese and weste rn medicine(TCM WM) on lung fibrosis in recovery stage in patients with severe a cute respiratory syndrome(SARS). Methods: From June of 2003, a randomized, placebocontrolled, prospective clin ical trial was conducted. Thirtysix cases with fiber hyperplasia and pulmonary interstitial fibrosis showed by CT were randomly divided into two groups. Seventeen c ases of the pure traditional Chinese medicine treatment group were treated with traditional Chinese herb com posite 861 medicinal granules(复方861冲剂) orally, and 19 cases of TCM WM gr oup were treated w ith composite 861 medicinal granules and Nacetylcysteine simultaneously. The abnormal indexes of ser ology, etiolog y and immun ology examed at the first time were measured at 1 st and 3 rd month after treatment, and the changes of fiber hyperplasia were observed by pulmonary C T. Results: The total efficiency rate of antifibrosis treatment in two groups we re 600%( 9/15 cases) and 647%(11/17 cases), respectively. There was no si gnificant diffe rence between two groups. Conclusion: The treatment of Chinese herbal composite 861 medicinal granules has the e ffect of reducing the use of western medicine, decreasing the cost for disea se.