Honey on healing of foot ulcer in diabetic patients

INTERVENTION: In experimental group daily dressing will be performed after washing the wound with normal saline. Then with a piece of gauze that is about 2 cm larger than the size of the wound, honey will be applied, and the wound will be dressed. Spring honey that will be used in this study approved by food laboratory of Mazandaran University of Medical Sciences as PH, amount of Froctos and absence of micro‐organisms . In the control group after washing the wound with normal saline, a layer of sock gauze will be applied on wound and with minimal pressure the wound will be bandaged. Wound dressing will be done daily with a trained nurse and control of it's recovery will be followed by orthopedic surgeon. Intervention 1: In experimental group daily dressing will be performed after washing the wound with normal saline. Then with a piece of gauze that is about 2 cm larger than the size of the wound, honey will be applied, and the wound will be dressed. Spring honey that will be used in this study approved by food laboratory of Mazandaran University of Medical Sciences as PH, amount of Froctos and absence of micro‐organisms . Intervention 2: In the control group after washing the wound with normal saline, a layer of sock gauze will be applied on wound and with minimal pressure the wound will be bandaged. Wound dressing will be done daily with a trained nurse and control of it's recovery will be followed by orthopedic surgeon. Treatment ‐ Drugs CONDITION: (I79.2*) Diabetic peripheral angiopathy diabetic foot ulcer. ; Diabetic peripheral angiopathy PRIMARY OUTCOME: Diiabetic foot ulcer. Timepoint: Befor study and at the end of the first, second and third week after intervention. Method of measurement: Researcher made list. SECONDARY OUTCOME: Gangrene or amputation. Timepoint: Every day until the end of the study. Method of measurement: ?Assesment and report by a specialist nurse. INCLUSION CRITERIA: INCLUSION CRITERIA: ulcer diabetic type 2 and 3 ; absence of vascular disease Exclusion criteria; rheumatoid arthritis, vasculitis, chemotherapy, immunosuppressive and steroid drugs drugs affecting the nerves and blood vessels, such as anticonvulsants and anti‐arrhythmias