Phase III Study Treatment of CLL B and C

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2007
GOELAMS LLC98 is a prospective randomized trial comparing in previously untreated B and C Binet stages B-CLL and on an intent to treat basis two strategies. Conventional chemotherapy consisted of six monthly courses of CHOP, followed by 6 CHOP courses every other 3 months in case of response. Experimental arm consisted of high dose therapy with autologous CD34+ purified progenitor cell support, used as consolidation of Complete Remission or Very Good Partial Response obtained after 3 monthly courses of CHOP, followed by 3 to 6 monthly-courses of fludarabine in case of insufficient response.
Epistemonikos ID: 2f3c8f372c999522d3515d377899d059496e2a9f
First added on: Jan 21, 2022