Safety, Tolerability and Pharmacokinetic of Recombinant Anti-IL-5 Humanized Monoclonal Antibody Injection

The requested reference [f05e1287d6200f70d9cf82098b15acdaff4f7d8f] no longer exists in our database. It has been replaced by the current reference: [f1349c9cd1b042ec8ccd02a0c12de199b8812aa4]

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2020
This study is Safety, Tolerability and Pharmacokinetic of Recombinant anti-IL-5 Humanized Monoclonal Antibody injection in Healthy Subjects. There are 6 Groups as follows: 0.03mg/kg (S1), 0.2mg/kg (S2), 1.0mg/kg (S3), 3.0mg/kg (S4), 5.0mg/kg (S5) and 7.5mg/kg (S6); and 2 subjects were included in the S1 group (both received study drugs); 10 subjects were included in each of the S2 \~ S6 groups (of which 8 received study drugs and 2 received placebo). Pharmacokinetics and Anti-drug antibody (ADA) data will be collected; Drug safety, tolerance, efficacy and immunogenicity for healthy subjects will be evaluated.
Epistemonikos ID: 2d5593538e478634b868f3f8d5da921b0969f44d
First added on: May 07, 2024