The London East Anglia randomised controlled trial for cognitive-behaviour therapy for psychosis: effects of the treatment phase

INTERVENTION: Participants randomised into the treatment group received up to nine months of individual cognitive behaviour therapy for psychosis. Sessions were conducted weekly initially, and then fortnightly. Participants randomised into standard care received routine care from their clinical team, which as part of the study entry criteria consisted of case management and medication. CONDITION: Schizophrenia and other psychoses ; Mental and Behavioural Disorders ; Schizophrenia PRIMARY OUTCOME: Measures were taken at baseline of demographic, clinical and cognitive variables. Changes over time were assessed on the Brief Psychiatric Rating Scale and the relationship between potential predictor variables and outcome was investigated using analysis of variance and covariance. SECONDARY OUTCOME: Not provided at time of registration INCLUSION CRITERIA: 60 participants who each had one positive and distressing symptom of psychosis that was medication resistant (28 in a treatment group received a cognitive behaviour therapy and 32 a standard care only control condition).