Clinical Efficacy and Brain Functional Mechanisms of Jin's Three-Needle Therapy for Post-Stroke Fatigue: A Randomized Controlled Trial

Authors
Category Primary study
Registry of TrialsInternational Traditional Medicine Clinical Trial Registry
Year 2026
INTERVENTION: Acupuncture Group : Jin's Three‐Needle Therapy;Sham Acupuncture Group:Sham Acupuncture; CONDITION: Post‐Stroke Fatigue PRIMARY OUTCOME: Fatigue Severity Scale (FSS‐7); SECONDARY OUTCOME: Multidimensional Fatigue Scale (MFI‐20);modified Rankin Scale (mRS);Energy Domain of the Stroke‐Specific Quality of Life Scale (SS‐QOL);Patient Health Questionnaire‐9 (PHQ‐9);Functional Independence Measure (FIM);Resting‐state functional magnetic resonance imaging (rs‐fMRI); INCLUSION CRITERIA: Diagnostic Criteria for Post‐Stroke Fatigue (PSF) Stroke patients who meet the following criteria: (1) Persistent fatigue occurring daily or almost daily for at least 2 weeks within the recent month, characterized by exhaustion or significant fatigue with decreased energy as the predominant features, requiring increased rest time, and disproportionate to physical or mental exertion; (2) Presence of the above symptoms plus any 3 of the following: 1) Fatigue not effectively relieved or restored by sleep or rest; 2) Motivation for rehabilitation exercises remains but efficiency declines; 3) Motor weakness requires continuous self‐cognitive effort to overcome; 4) Difficulty initiating or maintaining daily activities due to subjective fatigue; 5) Post‐exertional discomfort lasting several hours or longer; 6) Obvious preoccupation with fatigue sensations. Inclusion Criteria 1) Patients meeting the above diagnostic criteria for PSF;
Epistemonikos ID: 2bfc955c28f6d2e38fd5367924b7b134e94b9923
First added on: Aug 08, 2026