Comparison of Two Different Doses of Dexamethasone with ropivacaine for Pain Relief after surgery in patients undergoing Laparoscopic Gallbladder Surgery

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Ropivacaine plus Dexamethasone: Group RD1 (Ropivacaine + Dexamethasone) Ropivacaine ( 0.5%,10ml) Dexamethasone 4mg (1ml) NS (0.9%,9ml) Total dose [ 20ml (0.25% ropivacaine on each side ] Control Intervention1: Ropivacaine plus Dexamethasone: Group RD2 (Ropivacaine + Dexamethasone) Ropivacaine ( 0.5% ,10ml) Dexamethasone (8 mg ,2ml) NS (0.9%,8ml) [Total dose‐20ml (0.25% ropivacaine ) on each side ] CONDITION: Health Condition 1: PCS‐ PRIMARY OUTCOME: Duration of postoperative analgesia measured as the time from administration of ultrasound guided transversus abdominis plane block to the first rescue analgesiaTimepoint: Within 24 hours after surgery SECONDARY OUTCOME: Hemodynamic parameters including Heart rate, systolic blood pressure and diastolic blood pressureTimepoint: At 2,6,12,24 hours after surgery Numeric rating scale score for postoperative painTimepoint: At 2,6,12 and 24 hours after surgery Total diclofenac consumptionTimepoint: Within 24 hours after surgery Total paracetamol consumptionTimepoint: Within 24 hours after surgery Total tramadol consumptionTimepoint: Within 24 hours after surgery INCLUSION CRITERIA: Age between 18 to 65 years American Society of Anesthesiologist physical status I and II Patient posted for elective laparoscopic cholecystectomy Ability to understand the study protocol and provide informed consent
Epistemonikos ID: 2bb35625d47dc0cd41913030b16451c5070969e6
First added on: Oct 08, 2026