Comparison of efficacy and safety of endoscopic band ligation combined with 1% lauromacrogol versus 3% polidocanol for grade II–III internal hemorrhoids: a single-center, prospective, outcome-assessor-blinded randomized controlled trial

INTERVENTION: Lauromacrogol combined ligation group:Endoscopic rubber band ligation combined with injection of 1% lauromacrogol foam sclerosant;Polidocanol combined ligation group:Endoscopic rubber band ligation combined with injection of 3% polidocanol foam sclerosant; CONDITION: Grade ?–? internal hemorrhoids PRIMARY OUTCOME: Quality of life score;Treatment Success Rate; SECONDARY OUTCOME: Goligher Classification of Internal Hemorrhoids;Hemorrhoidal Disease Symptom Score, HDSS;Wexner Constipation Scoring System;Visual Analogue Scale, VAS;Disease Recurrence Rate;Adverse Event; INCLUSION CRITERIA: 1. Patients with symptomatic grade ?–? internal hemorrhoids who failed conservative treatment. The grading of hemorrhoids is determined by experienced gastroenterologists based on symptoms and digital anal examination results. 2. Patients voluntarily participate in the study, agree to follow‐up, can objectively describe symptoms, actively cooperate with scale completion, and sign informed consent.