Unlocking Healing: Ozone Therapy's Breakthrough in Oral Lesion Management - A Narrative Review.

Ozone therapy, a versatile and potent treatment option, is garnering attention for its efficacy in managing various oral lesions. By conducting a comprehensive literature search without timeline restrictions across databases such as PubMed, Scopus, and Web of Science, this review synthesizes findings from randomized controlled trials, cohort studies, and significant case reports. The results indicate that ozone therapy effectively reduces microbial load, enhances wound healing, and alleviates pain, thereby improving overall treatment outcomes. This review compares ozone therapy to traditional treatment modalities, highlighting its potential for reducing dependence on pharmacological treatments due to its minimal side effects and significant efficacy. The integration of ozone therapy into mainstream dental practices is discussed, along with the barriers such as regulatory issues and the need for further research.