Phase II double blind trial of PC-SOD in patients with idiopathic interstitial pneumonias

INTERVENTION: Intravenous infusion of 40mg of PC‐SOD(lecithinized superoxide dismutase) is administered over 1 hour once a day for consecutive 28 days. Intravenous infusion of 80mg of PC‐SOD(lecithinized superoxide dismutase) is administered over 1 hour once a day for consecutive 28 days. Intravenous infusion of placebo of PC‐SOD(lecithinized superoxide dismutase) is administered over 1 hour once a day for consecutive 28 days. CONDITION: Idiopathic interstitial pneumonias(GradeIII to IV) PRIMARY OUTCOME: Forced Vital Capacity(FVC) INCLUSION CRITERIA: 1)Patients confirmed idiopathic interstitial pneumonias by X‐ray and HRCT 2)Patients with Grade III to Grade IV idiopathic interstitial pneumonias and possible measurement of vital capacity 3)Patients must be in hospital during the period of the clinical trial. After the trial, they will be consulted in hospital or as outpatients. 4)Patients who personally give informed consent in writing