The effect of toothpaste with active oxygen in reducing of dental plaque.

Authors
Category Primary study
Registry of TrialsBrazilian Registry of Clinical Trials
Year 2016
INTERVENTION: D25.376.711 E05.318.308.980.438.300.300 It will take 48 students of dentistry for the study aged between 18 and 35 years. These volunteers should be 7 to 10 days without brushing their teeth to develop gingivitis. After gingivitis established,participants are randomly divided into two groups A and B with 24 participants each. Participants in Group A (n = 24) will receive toothpastes containing hydrogen peroxide, sodium perborate, honey, xylitol and lactoferrin and toothbrush. Group B (n = 24) will receive dentifrice containing 0.3% triclosan, 2% copolymer and 0.243% (1.100 ppm) of sodium fluoride and toothbrush. Participants will bruch their teeth only with toothpaste and brush supplied by the study. Participants will come back to follow up the 1st 12 ° and 18 ° week to evaluate the gingival Index and plaque and check the commitment. O study ends after 18 weeks. V02.550 CONDITION: C07.465.714 C07.465.714.258.480 Gingivitis, Periodontal Disease ; C07.465.714 ; C07.465.714.258.480 PRIMARY OUTCOME: Low plaque scores after using the toothpaste containing hydrogen peroxide, sodium perborate, honey, xylitol and lactoferrin, observed by plaque indice. SECONDARY OUTCOME: Reduction of sites with gingival bleeding observed by scores of Gingival Index. INCLUSION CRITERIA: Healthy volunteers; aged between 18 and 35 years; a minimum of 28 teeth; no dental cavities; no periodontitis and established gingivitis.
Epistemonikos ID: 2ae37ebaa94825d3ad48892483bacc048b4a2d03
First added on: Aug 24, 2024