A clinical trial evaluating of effect of Descurainia sophia (L.) on clinical symptoms of adult patients with functional constipation

INTERVENTION: Intervention: A spoonful of dry seeds of Descurainia sophia L. and a spoonful of sugar in a cup of boiling water are mixed and taken at fasting once a day. If the properties of defecation do not satisfy the patient , he is allowed to increase the dose of drug every three days to a maximum of 6 teaspoons / day. Intervention: A spoonful of dry seeds of Descurainia sophia L. and a spoonful of sugar in a cup of boiling water are mixed and taken at fasting once a day. If the properties of defecation do not satisfy the patient , he is allowed to increase the dose of drug every three days to a maximum of 6 teaspoons / day.. Treatment ‐ Drugs CONDITION: Relationship of Descurainia sophia L. with functional constipation in adults. PRIMARY OUTCOME: The proportion of patients reaching three or more spontanouse complete bowel movement/week. Timepoint: At the begining, before the intervention and 4 weeks after, at the end of study. Method of measurement: By interviews with patients and asking them. SECONDARY OUTCOME: The number of laxatives used. Timepoint: At the begining, before the intervention and 4 weeks after, at the end of study. Method of measurement: By interviews with the patients and asking them. The score of a check list of Patient Assessment of Constipation Symptoms (PAC‐SYM) items. Timepoint: At the begining, before the intervention and 4 weeks after, at the end of study. Method of measurement: By interviews with the patients and asking them. The type of stool according to Bristol chart. Timepoint: At the begining, before the intervention and 4 weeks after, at the end of study. Method of measurement: By interviews with the patients and asking them. INCLUSION CRITERIA: INCLUSION CRITERIA: Age: 70‐20 years at the time of screening; Ability to participate in the study and there is no obvious behavioral disorders, speech and language diaeres; No major abdominal surgery; Lack of self and family history of thyroid disease; Colon cancer screening in people over 50 years; Lack of warning signs (rectal bleeding and weight loss and anemia); No underlying disease affecting constipation (Parkinson, Multiple sclerosis, stroke, hypothyroidism, cancer); Lack of pregnancy or lactation; Speaking ins; Avoiding the use of antibiotics in the past 5 weeks; Not taking medications causing constipation; No addiction; Complete the consent form; Having normal routine tests, including complete blood count, fecal occult blood test, alkaline phosphatase and TSH test, liver enzymes and Cr; No previous sensitivities to herbal medicines; Absence of severe cardiovascular disease, especially functional class 3 & 4 of chronic heart failure; Lack of proven malign