Pioglitazone Therapy Targeting Fatigue in Breast Cancer

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2021
The goal of this project is to evaluate the therapeutic potential of pioglitazone (PIO) to target underlying mechanisms that promote muscle fatigue in patients with breast cancer. This represents an off-label use of this compound, both in terms of the patient population and the clinical phenotype targeted. The central research hypothesis of this study is that daily pioglitazone will restore transcriptional downregulation of pathways within skeletal that promote fatigue.
Epistemonikos ID: 2a54b4574a1fdbca6224003375434ae2a64b698d
First added on: May 09, 2024