A study to assess the effects of Rapid Recovery on the adverse effects of alcohol consumption

Category Primary study
Registry of TrialsANZCTR
Year 2018
INTERVENTION: 750mg once daily Administration over two days 2 capsules first dose at the end of the consumption of alcohol 2 capsules the second dose the following morning First dose given at site by site staff. Second dose recorded by patient time and date and returned to staff the following day There is a seven day washout period Each capsule contains l‐cysteine hydrochloride 80mg, ascorbic acid 400mg, thiamine hydrochloride 80mg, pyridixine hydrochloride 20mg Alcohol was consumed 1.3 mg per kilogram for each participant all drinks had the time and amount recorded so that they could be repeated on the following study day CONDITION: hangover; ; hangover Metabolic and Endocrine ‐ Normal metabolism and endocrine development and function PRIMARY OUTCOME: Validated questionnaire for Hangover Symptom Severity.; As described by Hogewoning et al overall hangover severity was measured using a single one‐item rating and severity of 23 hangover symptoms that was rated on an 11‐point Likert scale ranging from 0 to 10. The 23 items were derived from the Alcohol Hangover Severity Scale, the Hangover Symptoms Scale, and the Acute Hangover Scale. ; ; [all scientific data was collected the day following the alcohol consumption.] SECONDARY OUTCOME: High sensitivity C reactive protein and Gamma GT this is a composite secondary outcome looking at these two inflammatory markers. by serum analysis.[Baseline, visit 1 and Visit 2] simulated driving ability. This will be assessed using Schuhfried driving/cognitive testing computer. This is a validated assessment of driving ability.[one day after the first dose] INCLUSION CRITERIA: Normal males and females who have suffered a hangover in the previous year
Epistemonikos ID: 2a14755ff744f61a1d708126cc6c56db4bad73c9
First added on: Aug 24, 2024