Mentha Piperita in the management of oesophageal soft food bolus impaction

Authors
Category Primary study
Registry of TrialsANZCTR
Year 2021
INTERVENTION: Patients presenting with food bolus, will have endoscopy performed by a gastroenterologist or gastroenterology trainee under the supervision of a gastroenterologist. Patient with food bolus distance > 20 cm from incisors will be randomized to receiving either the study drug (2%peppermint oil) or placebo. This will be instilled at an initial volume of 10mls and delivered endoscopically, followed by a further 10mls one minute later if there is no spontaneous resolution of the food bolus. Should there be no spontaneous passage of SFBO one minute after the second administration then a gentle push technique will be trialled. If the push technique fails, then retrieval of the SFBO will be using equipment at the discretion of the endoscopist. The total duration of the endoscopy is one of the end points that will be measured. Should the peppermint prove successful then the duration of endoscopy in the study arm will be significantly shorter. Difficult food bolus obstruction can sometimes take over 2 hrs to disimpact. Adherence to intervention will be monitored by documentation during procedure. CONDITION: Oral and Gastrointestinal ‐ Other diseases of the mouth, teeth, oesophagus, digestive system including liver and colon Soft food bolus obstruction (SFBO) ; ; Soft food bolus obstruction (SFBO) PRIMARY OUTCOME: Ability of Mentha Piperita to shorten duration of endoscopic procedure. The total procedure time is recorded on the reporting software. The procedure start and end times are bookmarked by the nurse on this software (i.e "scope in" and scope out" times) during the procedure.[At time of endoscopy ] SECONDARY OUTCOME: Ability of Mentha Piperita to cause spontaneous passage of food bolus. This will be recorded on a data collection sheet by the endoscopist.[At time of endoscopy ] Ability of Mentha Piperita to improve success of push technique for SFBO. This will be recorded on a data collection sheet by the endoscopists. I.e was the food bolus able to be pushed into stomach if it failed to pass spontaneously or did it require extraction using other instruments.[At time of endoscopy] INCLUSION CRITERIA: All patients presenting to Logan hospital, 18 years of age with an oesophageal food bolus obstruction will be considered for the study.
Epistemonikos ID: 29f94ff8ea82a055acfe64fe6502795081a00ce3
First added on: Aug 25, 2024