To determine the efficacy and safety of diclofenac topical solution in comparison with topical diclofenac gel in acute painful musculoskeletal conditions

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2010
INTERVENTION: Intervention1: Diclofenac topical solution: 4 times a day for 7 days Control Intervention1: Diclofenac Gel: 4 times a day for 7 days CONDITION: In acute painful musculoskeletal conditions PRIMARY OUTCOME: 50% pain reduction at 7 days.‐‐‐‐‐‐Timepoint: End of the study visit SECONDARY OUTCOME: Degree of functional impairment‐‐‐‐‐‐Timepoint: End of study visit Degree of local signs (Swelling, Tenderness)‐‐‐‐‐‐Timepoint: End of study visit Need for rescue analgesia‐‐‐‐‐‐Timepoint: During entire study period Pain intensity at rest and passive movement‐‐‐‐‐‐Timepoint: On day 3 and End of study visit Patients & Physicians global assessment‐‐‐‐‐‐Timepoint: End of study visit INCLUSION CRITERIA: 1. Male or females patients aged 18‐ 70 years. 2.Patients with acute low back ache (non‐ specific) or pain and inflammation following trauma to muscles/ tendons/ ligaments/ joints (due to strains, sprains, stress, soft tissue injuries or blunt sports injuries) for not more than 2 days 3.Patients with at least moderate pain of VAS ≥ 4
Epistemonikos ID: 29f6de5159cddc970121d7fad11fc7e99198b558
First added on: Aug 22, 2024