Testing a new approach for modifying the characteristics of the gums

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2023
INTERVENTION: In this split‐mouth study, individuals with thin gingival phenotypes were randomly treated with a connective tissue graft and an albumin gel‐platelet‐rich fibrin mixture (Alb‐PRF). Allocation will be at random using a sequentially numbered opaque, sealed envelope method. The connective tissue graft will be applied at the gingiva on one side of the mandibular anterior region, and Alb‐PRF will be applied on the other side for the same patient. Clinical measurements will be taken every month during the 3‐month follow‐up period. CONDITION: Thin gingival phenotype ; Oral Health PRIMARY OUTCOME: ; 1. Gingival thickness measured using a no.15 endodontic spreader (inserted perpendicularly from the vestibular midpoint 1.5 mm apical of the gingival margin through the soft tissue until a hard surface is reached) and a digital caliper to assess the penetration depth at baseline, 1, and 3 months; 2. Keratinized tissue width measured from gingival margin to mucogingival junction with the help of a periodontal probe (UNC 15 probe) at baseline, 1, and 3 months; SECONDARY OUTCOME: ; 1. Probing depth inde Xmeasured using a periodontal probe to measure the periodontal pocket depth at baseline, 1, and 3 months; 2. Relative attachment level measured using a UNC‐15 probe at baseline, 1 and 3 months; 3. Pain measured using a visual analogue scale (VAS) at 1 week after surgery; 4. Healing measured using a healing inde Xat 1, 2 weeks and 1 month after surgery; INCLUSION CRITERIA: 1. Systemically healthy patients 2. Gingival thickness of the mandibular anterior teeth >1 mm 3. No pregnancy or lactation 4. Non‐smokers 5. Adequate plaque control 6. At least 18 years of age 7. No previous periodontal surgery in the area
Epistemonikos ID: 28433674cf15895a7370d71c20f5e13e2b41b83b
First added on: Feb 20, 2024