مقايسه تأثير تحريك نوك پستان و انفوزيون سنتوسينون بر القاي زايمان و پيامدهاي آن در زنان نخست زا.

Background and AIM: Syntocinon is one of the most well-known drugs for labour induction. Considering the side effects of it, attention increased to the physiological and non-pharmacological methods like nipple stimulation. The aim of this study was to compare the effect of nipple stimulation as a natural method and syntocinon infusion as a medical method for the induction of labor and its outcomes. MATERIALS AND METHODS: This was a randomized controlled clinical trial that was performed in the maternity ward of Hazrat Zainab hospital of Babolsar in 2012. 132 primiparous women who were in 38-42 weeks gestational age with the indication for induction of labor participated in the study. Subjects were randomly assigned to nipple stimulation and syntocinon infusion groups. In the nipple stimulation group Unilateral stimulation of nipple performed for 15 minutes, which followed by 15 minutes rest up to six hours. If there were effective contractions and changes in bishop score during this period, stimulation continued up to delivery. In the control group 10 units of syntocinon added in one litter of Ringer's serum, and it was infused by 2.5 mU/min dosage. If there was no effective contraction, 2.5 mu/min was infused every 15 minutes up to 40 mU. If there were effective contractions and changes happened in Bishop's score, the infusion was continued until delivery. Data collection tools were demographic questionnaire, observation check list and Mcgill's pain scale. Data were analysed using statistical tests including Chi-square and t-test, with a significance level of p<0.05 by SPSS version 16. Result: The two groups were similar regarding demographic characteristics, gestational age and Bishop's score at the start of the study. The mean of initiation of effective uterine contractions in the Nipple stimulation group was 176.4 ± 0.47 minutes and in syntocinon group, it was 134.4 ± 0.7 (P = 0.000). Length of the first stage of labor was significantly shorter in the syntocinon group (p =0.001). There were not any significant differences between two groups in length of the second stage, tetanic contraction's prevalence, abnormal fetal heart rate, meconium staining and Apgar score. CONCLUSION: The findings of this study showed that nipple stimulation can be used as a safe method for ripening the cervix and induction of labor especially in the cases which syntocinon is contraindicated.