Periodontal Air-Polishing Device Versus Manual Scaling and Root Planing

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
This study looks at two common ways to perform deep cleaning of the gums in people with periodontitis: Airflow® (a spray system that uses fine powder and water) and hand scaling (cleaning with metal instruments). The investigators want to see how each treatment affects inflammation at the molecular level by measuring exosomes (tiny particles released by cells that carry signals) and cytokines (proteins that help regulate inflammation) in the fluid around the gums. Participants will receive one of the two standard treatments and will have samples taken from the mouth (saliva and/or gum fluid) at specific times before and after treatment. The authors will also record clinical measurements such as bleeding, gum pocket depth, and attachment loss, as well as simple questionnaires about symptoms.
Epistemonikos ID: 26f4661c870f5b3753037a500f9dd18f1187b704
First added on: Oct 02, 2025