Comparing how well arm numbness works when two anaesthetic drugs are given mixed together versus one after another, before arm and hand surgery

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Group S sequential injection: nerve‐stimulator‐guided supraclavicular brachial plexus block. 15 mL of 2 percent lignocaine with adrenaline 1:200,000 plus dexmedetomidine 0.5 g/kg injected first, followed 60 seconds later by 15 mL of 0.75 percent ropivacaine plus dexmedetomidine 0.5 g/kg. Total volume 30 mL, total dexmedetomidine 1 g/kg. Single administration, pre‐operative. Control Intervention1: Group M Mixture injection: nerve‐stimulator‐guided supraclavicular brachial plexus block.15 mL of percent lignocaine with adrenaline 1:200,000 and 15 mL of 0.75 percent ropivacaine combined as a 1:1 mixture with dexmedetomidine 1 g/kg, injected as a single 30 mL bolus. Single administration, pre‐operative. CONDITION: Health Condition 1: O‐ Medical and Surgical PRIMARY OUTCOME: Proportion of patients with complete sensory block.pinprick score 1 in all four nerves musculocutaneous, median, radial, ulnar.Timepoint: Proportion of patients with complete sensory block.pinprick score 1 in all four nerves musculocutaneous, median, radial, ulnar. SECONDARY OUTCOME: Onset time of block. Time to complete block.Duration of analgesia.Timepoint: from completion of injection until achieved.Time to complete assessed every 2 to 5 min up to 30 min.Duration assessed Up to 24 h post block.Duration of analgesia block completion to first rescue analgesic INCLUSION CRITERIA: Patients willing to sign the informed written consent. Patients of ASA Grade I and II of either gender. Undergoing elective upper‐limb surgeries.
Epistemonikos ID: 2624642df475ea2fb9a34bb1c0fc2e305b2d750b
First added on: Oct 08, 2026