Use of ozone for tooth whitening in patients with tooth sensitivity: clinical and randomized study

Authors
Category Primary study
Registry of TrialsBrazilian Registry of Clinical Trials
Year 2025
INTERVENTION: The present study aims to be a double‐blind randomized clinical trial (the patient will be blinded by means of completely dark glasses and the study evaluator, who will not know which of the techniques will be used). The control group: will have 21 patients and seeks to evaluate the performance of 35% hydrogen peroxide applied in the control group for 45 minutes, using a desensitizer based on 5% Potassium Nitrate with 2% Sodium Fluoride prior to the bleaching agent for 10 minutes, while in the test group: there will be 21 patients and ozonized gas will be used at a concentration of 30 µg will be applied for 30 minutes compared to the test group that will be used ozonized gas will be subjected to an impression with alginate and the creation of the plaster model. In the plaster model, a relief will be made with three layers of aluminum foil on the surface of the anterior teeth that will be whitened. Next, a rigid and transparent polyethylene terephthalate tray will be made (Bio‐art, São Carlos, SP, Brazil). After finishing and cutting the tray, the aluminum will be removed, providing space for the action of the ozonized gas. After making the tray, two holes will be made on the buccal side for entry and one hole on the palatal side for the exit of the ozonated gas. Both the test group and the control group will have a single session. The group randomization process will be done using envelopes with letters A and B with the same quantity, sealed, which will be opened at the time of the procedure CONDITION: C07.793.929 Dentin Sensitivity PRIMARY OUTCOME: Demonstrate the reduction of tooth sensitivity through ozone therapy in patients with hypersensitivity. SECONDARY OUTCOME: Determine whitening protocol in patients with dentin sensitivity using ozone therapy Evaluate color change during ozone therapy treatment To compare the pain perception of the gold standard of whitening with ozone therapy in dentin sensitivity INCLUSION CRITERIA: Patients of both sexes will be included in the study; aged between 18 and 35 years; with all vital anterior teeth; never whitened or restored; with periodontal health; no history of spontaneous dental pain; that do not use toothpaste with desensitizing properties; with grade 1 to 3 dentin sensitivity; willing to return for future evaluations during the research period
Epistemonikos ID: 253693317e3c1f5f2bb16abd5444dbf7739537b1
First added on: Apr 02, 2025