Clinical Trial of a Paste Endodontic based on calcium hydroxide and Aloe Vera

INTERVENTION: Behavioural Drug Fifty participants will be selected who have a uniradicular tooth (teeth with a single root) with pulp necrosis and presence of periapical lesion, in need of endodontic treatment. Participants will be randomly allocated to two groups according to the intracanal medication that will be used during the treatment: 25 patients will compose the experimental group, and will use the Calcium Hydroxide paste pa and Aloe Vera gel as intracanal medication and 25 patients will form the control group , the intracanal medication being the paste of Calcium Hydroxide and distilled water. The research operator will be the same for all patients, in order to maintain the standardization of procedures. For the endodontic treatment, coronary opening, irrigation with 2.5% sodium hypochlorite and the introduction of files using the modified Oregon technique will be performed. The intracanal medication will then be placed inside the root canals according to the specificities of each material. For the Experimental Group, each affected tooth will receive, as an intracanal medication, Aloe vera gel (obtained from the plant leaf Aloe barbadensis Miller, at the Nucleus for Research in Medicinal Plants at the Federal University of Piauí, as an intracanal medication, and filtered through a 25 mm PureFlo Disc Filter. and micragem equal to 5 mm.) and Calcium Hydroxide P.A. in the powder / diluent ratio specified by the manufacturer. In the control group, each affected tooth will receive as a intracanal medication a paste made with Calcium hydroxide PA and distilled water, in the powder / diluent ratio specified by the manufacturer. In the same session, the tooth will be provisionally restored with glass ionomer cement, and maintained for 15 days, after which, in all teeth, intracanal medications will Procedure/surgery Pulp Capping and Pulpectomy Agents Root Canal Preparation CONDITION: Endodontics Endodontics; Root Canal Therapy ; Endodontics ; Root Canal Therapy R00‐R99 Root Canal Therapy PRIMARY OUTCOME: The presence of similar postoperative pain in both groups, with greater radiographic scarring in the group receiving intracanal medication of Aloe Vera and Calcium Hydroxide The presence of pain will be assessed by means of an analogue scale at three different times and the results will be presented through statistical analysis for comparison between the groups. SECONDARY OUTCOME: Secondary outcomes are not expected INCLUSION CRITERIA: Healthy volunteers aged 18 to 65, with at least an anterior tooth with apical periodontitis between 01 mm by 01 mm and 05 mm by 05 mm, requiring endodontic treatment.