Mind-Body Interventions in Coronary Artery Disease

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This study is a prospective, randomized controlled clinical trial designed to evaluatethe effects of a structured mind‐body intervention on psychological outcomes in patientswith stable coronary artery disease.Eligible participants will be recruited from Ufuk University Department of Cardiology andrandomly assigned to either an intervention group or a control group using a simplerandomization method. The intervention group will receive eight individualized sessionsof progressive muscle relaxation and guided imagery over a four‐week period in additionto standard medical care. Each session will last approximately 45‐60 minutes and will beconducted in a controlled clinical environment by trained researchers. The control groupwill continue receiving standard medical care without any additional psychological orbehavioral intervention.Outcomes will be assessed at baseline and post‐intervention using validated self‐reportinstruments, including the Perceived Stress Scale (PSS), Hospital Anxiety and DepressionScale (HADS), and COPE Inventory. The primary outcome is change in perceived stresslevels. Secondary outcomes include changes in anxiety, depression, and coping strategies.Data will be analyzed using repeated measures ANOVA to examine the interaction effectsbetween group (intervention vs control) and time (baseline vs post‐intervention). Effectsizes will be reported, and statistical significance will be set at p < 0.05.The study does not involve any investigational drugs, biologics, or medical devices, andposes minimal risk to participants.
Epistemonikos ID: 237e96254ee9b40476d323a7cbff16a115723a43
First added on: Jun 09, 2026