The Efficacy of MDI Treatment With an Optimization Algorithm Adjusting Basal-Bolus Parameters in Children and Adolescents With Type 1 Diabetes at a Diabetes Camp

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2018
The objective of this project is to compare our basal‐bolus optimization algorithm with physician adjusted basal‐bolus parameters using a randomized parallel clinical trial in children and adolescents at a Camp Carowanis. The investigators hypothesize that using this optimization algorithm will be non‐inferior to the physician‐adjusted basal‐bolus parameters regarding time spent in target glucose range (3.9 mmol/L ‐ 10mmol/L). Between 40 and 68 children and adolescent type 1 diabetes patients undergoing MDI treatment at Camp Carowanis will randomly undergo one of two interventions: 1. MDI with Physician Adjusted Basal‐Bolus Parameters: Participants will be wearing the Freestyle Libre glucose sensor (Abbott Diabetes Care). Participants will undergo their conventional multiple daily injection (MDI) therapy. At breakfast, the research team will download the sensor data. Camp physicians will review each participant's sensor and insulin data and make changes to their parameters based on their clinical judgement, as they would for all campers, regardless of study participation. These new parameters will be entered into the patient's camp file. 2. MDI with Basal‐Bolus Optimization Algorithm Adjusted Basal‐Bolus Parameters: Participants will be wearing the Freestyle Libre glucose sensor (Abbott Diabetes Care). At breakfast, the data from the glucose sensor and injection information will be entered into a computer and the optimization algorithm will be run. Camp physicians will review the algorithm's recommendations before they are entered into the patient's camp file.
Epistemonikos ID: 22dde237ec8fb60cf806d9ca9bd0ce99ef190057
First added on: May 21, 2024