Clinical isolate of Citrobacter freundii highly resistant to new quinolones.

Category Primary study
JournalAntimicrobial agents and chemotherapy
Year 1988
About 30% of 150 recent clinical isolates of Citrobacter freundii were resistant to greater than or equal to 3.13 micrograms of norfloxacin and ofloxacin per ml. Study of one quinolone-resistant strain for which the norfloxacin MIC was 100 micrograms/ml suggested that resistance was associated with both an altered A subunit of DNA gyrase and reduction in drug uptake accompanied by a decrease in an outer membrane protein.
Epistemonikos ID: 218725e86104fc1573be4ed3b5c53fa994ede1af
First added on: Jan 05, 2023