Effect of GRAPEX in treatment of COVID-19

INTERVENTION: Intervention 1: Intervention group: Patients receiving standard country protocol drugs with Grapex 200 mg twice a day until the patient's clinical symptoms improve . Intervention 2: Control group: Patients receiving standard country protocol drugs with placebo twice a day until the patient's clinical symptoms improve . CONDITION: covid19. ; Other coronavirus as the cause of diseases classified elsewhere PRIMARY OUTCOME: Time to clinical alternations defined as start of taking medication time to Discharge Time. Timepoint: The beginning of the study ,the seventh day, the fourteenth day, the twenty‐first day, the twenty‐eighth day. Method of measurement: Medical record. INCLUSION CRITERIA: Patients diagnosed with covid19 by positive PCR test. Patients diagnosed with covid19 by positive CT scan evaluation SECONDARY OUTCOME: Alanine amino transferase. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Alkaline phosphatase. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Arterial oxygen saturation. Timepoint: The beginning of the study ,the seventh day, the fourteenth day. Method of measurement: Blood sample. Aspartate amino transferase. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Blood pressure. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Clinical examination. BUN. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. C‐reactive‐protein. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Complete Blood Count. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Cough. Timepoint: The beginning of the study ,the seventh day, the fourteenth day. Method of measurement: Clinical observation and examination. Creatinine. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. INR. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Level of serum potassium. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Level of consciousness. Timepoint: The beginning of the study ,the seventh day, the fourteenth day. Method of measurement: Using the Glasgow Coma scale. Level of serum sodium. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Mortality rate. Timepoint: Daily. Method of measurement: Blood sample. Number of days of hospitalization. Timepoint: Daily. Method of measurement: Medical record. Partial Thromboplastin time. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. Prothrombin time. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample. SER. Timepoint: The beginning of the study and the time of discharge. Method of measurement: Blood sample.