The assessment of the therapeutic effect of bee propolis on oral Lichen Planus treatment.

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2021
INTERVENTION: Intervention 1: Intervention group: Group A consumes Propolis in the form of mouthwash with a dose of 500 mg, according to the manufacturer's instructions once or twice a day after brushing; First rinse the mouth with water or serum (normal saline) and then immediately use mouthwash with a plastic cup on the glass. Each mouthwash should last at least 2‐3 minutes. Avoid eating and drinking for 30 minutes after using the mouthwash. Intervention 2: Control group: Group B consumes placebo which is prescribed in the same form as the main drug and in the same way. Use mouthwash once or twice a day after brushing; First rinse the mouth with water or serum (normal saline) and then immediately use mouthwash with a plastic cup on the glass. Each mouthwash should last at least 2‐3 minutes. Avoid eating and drinking for 30 minutes after using the mouthwash. CONDITION: Lichen planus. PRIMARY OUTCOME: Extent of Atrophic areas: The area of Atrophic areas measured by caliper in square millimeters.Extent of Ulcerative areas: The area of the wound area measured by the caliper. Area of Keratotic areas: Area of Keratotic areas measured by caliper. Intensity of pain and irritation: The scale of pain and oral mucosa irritation that the patient reports according to VAS. Timepoint: At the beginning of study and a month after the start of the study. Method of measurement: To measure the area of the affected areas, the largest lesion diameters are measured by a caliper and their product is considered as the area of the target area. If the patient has similar lesions in several areas, the area of all these areas will be added together and this amount will be reported. The scale of pain and irritation is measured by the Visual Analogue Scale. This method of measurement asks the patient to rate their pain and irritation from 0 (with no pain and irritation) to 10 (the most severe pain and irritation). INCLUSION CRITERIA: Patients who are diagnosed with OLP by an oral specialist. People who have been willing to participate in the study and sign the informed consent form.
Epistemonikos ID: 1ff50e6e8ddc31285860637237ae65c5a3589088
First added on: Aug 25, 2024