Clomiphene Citrate Alone Versus Clomiphene Plus Metformin as First Line Approach for the Treatment of Anovulation in Infertile Patients With Polycystic Ovary Syndrome

The requested reference [ef0165f3cd14410f4fdad4725a0288b0dedca043] no longer exists in our database. It has been replaced by the current reference: [dfb8eb82ce199bcabce072d4b8aeb57baf1dee64]

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This study will compare the effectiveness of clomiphene citrate alone with clomiphene citrate combined with metformin for treating anovulation and infertility in women with polycystic ovary syndrome (PCOS). Women with PCOS who have difficulty becoming pregnant because they do not ovulate regularly will be enrolled in the study. Participants will be assigned to receive either clomiphene citrate alone or clomiphene citrate combined with metformin. The study will compare pregnancy and ovulation outcomes between the two treatment groups to determine whether adding metformin to clomiphene citrate improves the chances of conception in women with PCOS-related anovulatory infertility.
Epistemonikos ID: 1f3d41dfd7d6eefc91de515ec195876721857231
First added on: Oct 14, 2026