Effects of Treatment of Ascites by the ALFApump System on Renal and Circulatory Function

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2011
This is a single centre, prospective, uncontrolled study to include 12 consecutive patients with cirrhosis of the liver and recurrent or refractory ascites. The main aim (primary objective) of the study is to investigate the effect of treatment of ascites by the Sequana medical pump on the renal and circulatory function in patients with cirrhosis and recurrent or refractory ascites. The secondary objectives are the following: * To evaluate the efficacy of treatment for handling ascites, associated with changes in the body weight of patients and their requirements for evacuation paracentesis during follow-up. * To investigate the effects of treatment on bacterial translocation, by means of determining bacterial DNA. * To determine the incidence of complications associated with treatment in the course of follow-up. * To evaluate the effect of treatment on quality of life of the patients treated, evaluated in questionnaires entitled Short Form-36 and CLDQ (chronic liver disease questionnaire).
Epistemonikos ID: 1e80c735e0534e4a4b438a70697b36101c66e616
First added on: May 10, 2024