Resistance to antibiotics in clinical isolates of Escherichia coli producing and non-producing Extended Spectrum Betalactamases (ESBL) obtained from urine cultures in patients with urinary tract infection.

ObjectiveIdentify resistance patterns against various antibiotics in Escherichia coli producers and non-producers of extended spectrum beta-lactamases in urinary infections in a population of the Toluca Valley, Mexico IntroductionEscherichia coli is a bacterium that is part of the normal biota of the human being, but under certain conditions it can produce diseases such as gastrointestinal and urinary tract infections for which is the main responsible. Enterobacteriaceae such as Escherichia are extended spectrum betalactamases (ESBL) producers, which makes their treatment difficult due to a high rate of resistance to antibiotics. Methods155 samples were collected from patients with suspected urinary tract infection without exclusion criteria such as age or gender. Automated equipment was used for the identification of the etiological agent and sensitivity tests. For the determination of ESBL, the double disc technique was used. Results35 strains of Escherichia coli were obtained, of which 45.72 % have ESBL, these strains show 100 % resistance to betalactams, as well as high resistance to quinolones and tetracycline ranging from 70 to 100 %. On the other hand, the resistance shown by non-ESBL producing strains is variable both for betalactams and for other antibiotics. ConclusionTreatment for urinary tract infections has become increasily difficult due to the high rate of resistance to antibiotics, mainly ESBL-producing strains such as the E coli strains in the present study. Where high rates of resistance to different antibiotics used in clinical practice are shown.