Clinical efficacy of IORT on patients with unrectable pancreatic body-tail carcinoma: a randomized controlled trial

INTERVENTION: Unresectable pancreatic cancer in operation:IORT;Unresectable pancreatic cancer in operation:natural light ; CONDITION: pancreatic body‐tail carcinoma PRIMARY OUTCOME: Safety Assessment;Quality of life scores;disease free survival time;Postoperative survival time; SECONDARY OUTCOME: Safety Assessment; INCLUSION CRITERIA: 1. Male and female aged 18 to 70 years old; Patients who are clinically diagnosed as pancreatic body‐tail carcinoma have good body situation and basic normal nutrition condition. They haven't undergone any preoperative chemotherapy or radiotherapy. They haven't severe dysfunction of heart,l ung, liver and kidney, and no Jaundice, ascites, obstructive alimentary tract and acute infection. The routine blood test is normal with WBC>=4,000/mm3, Hb>=100g/L and plt>=100,000/mm3. The coagulation parameters are normal with PT, KPTT and TT in normal range. Quality of life grading (Karnofsky criteria) is over 80 scores. Operative endurance is good to endure operation and chemo‐radiotherapy; 2. Patients are able and willing to provide signed informed consent; 3. Unresectable pancreatic cancer in operation.