A multi-center, randomized, double-blind, placebo-controlled clinical trial to evaluate the effectiveness and safety of Kunxinning Granules combined with Fenton in the treatment of menopausal syndrome (kidney yin and yang deficiency syndrome)

INTERVENTION: experimental group:Kunxinning granules + femton;control group:Kunxinning granule simulator + femton; CONDITION: Menopausal syndrome PRIMARY OUTCOME: Modified Kupperman score; SECONDARY OUTCOME: Traditional Chinese Medicine Symptom Score;Serum FSH, LH, E2;Menopausal quality of life (MENQOL) scale;Pittsburgh Sleep Quality Inde X(PSQI) Score; INCLUSION CRITERIA: (1) Meet the diagnostic criteria of Western medicine for menopausal syndrome; (2) Traditional Chinese medicine syndrome differentiation is syndrome of kidney yin and yang deficiency; (3) Modified Kupperman scale score =16 points; (4) Voluntarily participate in this clinical trial, give informed consent and sign a written informed consent form.