Use of transdermal glyceryl trinitrate to reduce failure of intravenous infusion due to phlebitis and extravasation.

Authors
Category Primary study
JournalLancet (London, England)
Year 1985
Self-adhesive patches which release glyceryl trinitrate at a slow continuous rate or placebo patches were applied to the skin of patients distal to intravenous infusion sites in a double-blind manner. The frequency of infusion failure was three times lower with the glyceryl trinitrate than with placebo patches. The decrease was of similar magnitude whether failure was due to extravasation or phlebitis. Headaches were more common in patients with active patches but were relieved by simple analgesics.
Epistemonikos ID: 1d96d168f873546812bb2ea4112b61c981f293af
First added on: May 14, 2022