Prevention of Acute Pancreatitis after examination of the bile ducts using only guidewire versus guidewire and contrast

INTERVENTION: Comparison of two techniques: one group of patients will undergo CPRE (retrograde endoscopic cholangiopancreatography) with the use of guidewire technique (260 patients); another group of patients will undergo the ERCP procedure with the guidewire plus non‐iodized medium contrast technique (260 patients). D27.505.259.500 E04.210 Procedure/surgery CONDITION: acute pancreatitis ; C06.689.750 C06.689.750 PRIMARY OUTCOME: post ERCP pancreatitis incidence, measured by the number of patients who developed acute pancreatitis after ERCP ‐ acute pancreatitis will be considered typical abdominal pain associated with increased blood levels of amylase or lipase levels by at least 3 times the upper limit of normality, and / or characteristic radiological image of acute pancreatitis. SECONDARY OUTCOME: cannulation rate of the bile duct, measured by the number of times that the biliary way could be cannulated. pre‐cut rate, measured in the number of times the pre‐cut technique had to be performed to cannulate the bile duct. procedure time, measured in minutes. INCLUSION CRITERIA: Consecutive patients over 18 years of age who are referred to the Radiology Center of the São José Pavilion (Biliary Endoscopy Service of Santa Casa / UFCSPA) will be included to perform CPER that, after due explanations about the study, agree to participate and sign the term of free and informed consent.