Effect of electroacupuncture combined with individualized positive end-expiratory pressure on perioperative lung injury serum markers and inflammatory factors in elderly patients undergoing spinal endoscopy

Authors
Category Primary study
Registry of TrialsInternational Traditional Medicine Clinical Trial Registry
Year 2026
INTERVENTION: Fixed PEEP Group:with a PEEP of 5;Individualized PEEP Group:Individualized PEEP Titrated by Dynamic Compliance (Cdyn);Electroacupuncture Combined with Individualized PEEP Group:Electroacupuncture Combined with Cdyn‐Titrated Individualized PEEP; CONDITION: Lumbar Disc Herniation (LDH) PRIMARY OUTCOME: Soluble Receptor for Advanced Glycation End Products (sRAGE); Pulmonary Surfactant ;Clara Cell Secretory Protein (CC16);interleukin‐6;interleukin‐8;tumor necrosis factor‐alpha; SECONDARY OUTCOME: Oxygenation Inde X(OI);Respiratory Mechanics Parameters;Incidence of Postoperative Pulmonary Complications (PPCs);lung ultrasound score;intraoperative vasoactive agent use; INCLUSION CRITERIA: 1) American Society of Anesthesiologists (ASA) Physical Status Classification II–III; 2) Elderly patients (aged 60–80 years) scheduled for endoscopic spinal surgery under general anesthesia, with an estimated operative time =2 hours; 3) Understand the study content and sign the informed consent form.
Epistemonikos ID: 1cfd9fd14d0dff24d8494ba64fa9914dcf80f423
First added on: May 09, 2026