Randomized controlled study of early replacement with factor XIII for fistula after pancreatic surgery (FIPS)

INTERVENTION: Early replacement with coagulation factor XIII Replacement with coagulation factor XIII over 2 weeks after recovery of inflammation and alimentation CONDITION: Fistula after pancreatic surgery PRIMARY OUTCOME: The length of pancreatic fistula cure after the recovery of inflammation and alimination INCLUSION CRITERIA: 1) Patient with drain over 7 days for pancreatic fistula after pancreaticoduodenectomy or distal pancreatectomy 2) Coagulation factor XIII is 70% or less after postoperative day 7 3) CRP < 2mg/dl 4) Over 20 years old 5) Patients with written informed consent