Comparision of dexmedetomidine and fentanyl for maintaing blood pressure and heart rate during elective laparoscopic surgery.

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil CONDITION: PRIMARY OUTCOME: To compare the hemodynamic parameters like heart rate and mean arterial pressure using dexmedetomidine versus fentanyl infusion to tracheal intubation and following pneumoperitoneum in patients undergoing elective laparoscopic surgeries.Timepoint: Prior to infusion of study drug,10 min after study drug, After induction, Immediately after intubation, 5 min after intubation, Immediately after pneumoperitoneum, 5 min, 10 min, 15 min, 30 min,45 min, 60 min after pneumoperitoneum, 5 min after release of pneumoperitoneum, 5 min after extubation, 10 min after extubation. SECONDARY OUTCOME: To compare the sedation score between the two study drugs using Modified Ramsay Sedation Score. ; To assess for any side effects like bradycardia, hypotension, hypertension, nausea & vomiting if any.Timepoint: Modified Ramsay Sedation Score ; 10 minutes after completion of the study drug infusion. ; Adverse effects like bradycardia, tachycardia, hypotension, hypertension, nausea & vomiting will be ; continuously monitored & recorded throughout the intraoperative period & until 10 minutes after extubation. INCLUSION CRITERIA: 1.Adult patient aged 18‐60 years and of either sex. 2.Patients belonging to ASA physical status class 1 and class 2. 3.Patients scheduled for elective laparoscopic surgery. 4.Patients giving informed written consent.
Epistemonikos ID: 1ca41cc3655e4a8a8071c1c370dc881a153a3de1
First added on: Oct 08, 2026