Crossover trial of single ingestion of mulberry leaf extract on postprandial hyperglycemia in pre-diabetic subjects

INTERVENTION: Carbohydrate‐rich meal intake after ingestion of placebo; blood collection before and 30, 60, 90 and 120 min after the meal Carbohydrate‐rich meal intake after ingestion of mulberry leaf extract (low‐dose); blood collection before and 30, 60, 90 and 120 min after the meal Carbohydrate‐rich meal intake after ingestion of mulberry leaf extract (middle‐dose); blood collection before and 30, 60, 90 and 120 min after the meal Carbohydrate‐rich meal intake after ingestion of mulberry leaf extract (high‐dose); blood collection before and 30, 60, 90 and 120 min after the meal CONDITION: diabetes PRIMARY OUTCOME: Postprandial plasma glucose and serum insulin levels INCLUSION CRITERIA: Fasting plasma glucose in the range of 100‐140 mg/dl