Evaluation of magnesium effect in treatment of migraine

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2023
INTERVENTION: Intervention 1: Intervention group: Magnesium oxide 10 mg/kg in 1 or 2 divided dose for 3 months should be used. Generic Magnesium Oxide 250 mg tablets from Jalinus pharmaceutical company are used. patients are also provided with Propranolol 0.5 mg/kg/day. Intervention 2: Control group: Placebo with complete resemblance to magnesium oxide pills with similar usage order produced by the pharmaceutical laboratory of Shiraz school of pharmacy. patients are also provided with Propranolol 0.5 mg/kg/day. CONDITION: Migraine. ; Migraine PRIMARY OUTCOME: Frequency of migraine attacks per month. Timepoint: At the beginning; then, 4 weeks later; then, 12 weeks after the initiation. Method of measurement: Direct asking of the patient in the first visit; then, using migraine diary in the following visits. SECONDARY OUTCOME: Amount of analgesic medications used. Timepoint: First visit; 4 weeks later; 12 weeks later. Method of measurement: direct asking and migraine diary. Average duration of migraine attacks per month. Timepoint: First visit; 4 weeks later; 12 weeks later. Method of measurement: direct asking and migraine diary. Severity of pain during migraine attacks. Timepoint: First visit; 4 weeks later; 12 weeks later. Method of measurement: Wong‐baker scale. INCLUSION CRITERIA: Age from 6 to 18 years old Weight less than 90 Kg Diagnosed as migraine according to IHSC‐3 criteria At least 4 migraine attacks in month or 8 days‐of‐headache during at least 1 month ago
Epistemonikos ID: 1bd932f60726d42ae4848aa1ceded9ca98609dfd
First added on: Feb 20, 2024