A Randomized controlled trial comparing Topical use of Mupirocin versus Medihoney for the prevention of infection at Tenckhoff Exit Site in Peritoneal Dialysis Patients

INTERVENTION: Once daly application of Topical Medihoney (gauze pad) approximately10 mg ( size of a pea) at Peritoneal dialysis catheter exit site once daily (the medihoney dressing will be changed daily ) compared topical application of small amount Mupirocin using cotton bud to Peritoneal dialysis catheter exit site once daily ( 12 months ) CONDITION: Peritineal Dialysis patients PRIMARY OUTCOME: time to first episode of exit site infection,peritonitis or tunnel infection ‐whichever comes first ( clinical assessment and microbiolgy to confirm the infection) SECONDARY OUTCOME: a longer time to infection‐associated catheter removal ; lower catheter‐associated infection rates; ; Meausred by number of catheter removal due to infection a lower incidence of adverse reactions ( all adverse events will be recorded and compared between the 2 groups). ; Methods used will be questionarre and occurence of resistance ( Microbiology test) Secondary Endpoints : whether intervention results in: ; a longer time to first exit site infection ( clinical assessment / microbiology) whether intervention results in a longer time first episode of peritonitis (clinical assessment / microbiology) INCLUSION CRITERIA: 1. Patients on peritoneal dialysis.( Incident and prevalent) 2. Able to give informed consent