Clinical efficacy evaluation and metabolomics study of electroacupuncture combined with three-step pain relief therapy in the treatment of moderate to severe pain in hepatocellular carcinoma

INTERVENTION: Observation group:Basic treatment + Electroacupuncture treatment;Control group:Basic treatment + Placebo electroacupuncture treatment; CONDITION: Hepatocellular carcinoma PRIMARY OUTCOME: Effective rate of pain relief; SECONDARY OUTCOME: Assessment of pain degree;Number of bursts of pain;Analgesic dosage;Frequency of gastrointestinal side effects;Comprehensive evaluation of life quality;Fatigue degree assessment;Sleep conditions assessment;Biochemical detection;Metabolomics detection; INCLUSION CRITERIA: (1) Patients who meet the diagnostic criteria for hepatocellular carcinoma; (2) Age =40 years old and =80 years old, gender not limited; (3) Patients with Child‐Pugh grade A or B; (4) The NRS score is =4 points within 24 hours before screening; (5) Patients with an expected survival period of more than 3 months; (6) Clear consciousness, capable of assessing one's own pain and quality of life; (7) Those who understand and agree to participate in this study and sign the informed consent form.