BAriCitinib Healing Effect in earLy pOlymyalgia Rheumatica

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2020
Patients with recent PMR(6 months or less) with a PMR‐AS >17 and no oral or parenteral GCs during the past 2 weeks (at least) will be included. Treatment with oral baricitinib 4mg or placebo during 12 weeks and then, if PMR‐AS≤10, they will receive baricitinib 2 mg for 12 weeks and then will stop treatment. No rescue is allowed before week 4 (visit 3) but patients may receive up to 2 intra‐articular or soft tissue injections of GCs until week 4 according to investigator's opinion. From week 4 to week 12, steroids will be proposed as a rescue for both arms at investigators' discretion and according to PMR‐AS.
Epistemonikos ID: 1b1b2cd5b6855664654b90d1f96656259083da4a
First added on: May 22, 2024