Effects of SEvoflurane on Gas Exchange and Inflammation in Patients With ARDS (SEGA Study)

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2014
Numerous trials support the efficacy and safety of volatile anesthetic agents, namely inhalation of sevoflurane through dedicated devices, for the sedation of ICU patients. Several preclinical studies have shown that sevoflurane inhalation improves gas exchange and decreases pulmonary and systemic inflammation in experimental models of acute respiratory distress syndrome (ARDS). The purpose of our prospective monocentric, randomized, controlled trial is to evaluate the effects of an early 48-hour sevoflurane inhalation on gas exchange and inflammation in patients with ARDS.
Epistemonikos ID: 1a44318d9f5f41adb834bb197e75ccc0ea9a5569
First added on: May 11, 2024