Clinical Importance of Occult Suprapatellar Effusion in Knee Osteoarthritis

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
Small amounts of fluid in the knee joint may not always be visible during a standard ultrasound examination performed while the leg is relaxed. When the quadriceps muscle contracts, this fluid may move into the area above the kneecap and become visible. This finding is referred to in this study as occult suprapatellar effusion. The aim of this study is to determine whether occult suprapatellar effusion is associated with knee pain and physical function in people with knee osteoarthritis. Participants will undergo ultrasound examination first at rest and then during quadriceps contraction. Based on these findings, they will be classified as having effusion visible at rest, occult effusion visible only during muscle contraction, or no effusion in either condition. Knee pain, self-reported symptoms and function, and chair stand performance will be compared among these groups. The study will also examine whether greater effusion depth is associated with more severe pain, greater functional limitation, and poorer physical performance. No treatment will be assigned as part of the study.
Epistemonikos ID: 1a2b06e19192b52fdd9fa6f3b5bd0f24f8144f7d
First added on: Oct 16, 2026